Melanotan II, CAS 121062-08-6, >99% by HPLC (UV 220nm), White Lyophilized Powder — every batch ships with a specific Certificate of Analysis that names the HPLC and mass spectrometry methods used, so your receiving laboratory can align its own QC verification against the supplied chromatograms and spectra.
Batch-Specific Method Transparency — Every shipment of Melanotan II (CAS 121062-08-6) includes a certificate naming the exact HPLC conditions, enabling your QC laboratory to replicate the verification without guesswork.
| Parameter | Value |
|---|---|
| Chemical Identity | Melanotan II (CAS 121062-08-6) |
| Product Type | Peptide Raw Material |
| Appearance | White lyophilized powder |
| Purity | >99% by HPLC (UV detection at 220 nm) |
| Impurity Content | <0.1% |
| Endotoxin | ≤0.5 EU/μg |
| Form | Lyophilized Powder |
| Packaging Size | Available in 5 mg, 10 mg, 15 mg per vial |
| Container Type | Bottle/Box |
| Storage Temperature | -20 °C, sealed, light-protected |
| Shelf Life | 24 months (unopened, -20 °C) |
| Reconstituted Stability | Approximately 1 month at 4 °C, approximately 6 months at -20 °C |
| Certification | GMP, ISO 9001 |
| HS Code | 29371290 |
| Transport Condition | Cold chain, temperature-controlled packing with transit records |
| Use Category | Notes |
|---|---|
| Laboratory Research Input | Suitable as a receptor pharmacology research tool for melanocortin receptor studies (in vitro) |
| Analytical Reference | Batch-specific HPLC and MS documentation supports assay development and method validation |
| Peptide Structure-Activity Relationship Studies | Supplied at research and bulk scale for systematic structural investigation |
| Cosmetic Formulation Raw Material | Cosmetic-grade peptide ingredient for formulators requiring full analytical traceability |
Supplied as a raw material for research and manufacturing use. Not for human or veterinary use. Not a finished product.
A purity number without its method is an unverifiable claim. When receiving laboratories re-test Melanotan II using different column chemistry, mobile phase composition, or detection wavelength, the resulting chromatograms diverge — sometimes enough to trigger a batch rejection dispute that stalls projects for weeks.
I have watched this play out repeatedly: a supplier reports >99% by HPLC but omits the column type, gradient slope, and UV wavelength. The buyer’s QC runs their own method and sees extra peaks that the original certificate never captured. Neither party is wrong — the methods are simply not aligned. [NEED_CITE: ICH Q2 guidelines on analytical method validation for peptide characterization] The result is a month of emails, retesting, and eroded trust, all over a data gap that could have been closed before the vial left the warehouse.
Melanotan II purity HPLC analytical verification on this material is performed using reverse-phase chromatography with UV detection at 220 nm. The peptide bond absorbs strongly at this wavelength, making it a reliable detection point for both the main compound and low-level impurities. The chromatographic conditions — including column specification, mobile phase gradient, and flow rate — are recorded on every batch certificate so the receiving laboratory can reproduce the separation.
Purity alone does not confirm that the correct molecule is in the vial. Each batch certificate includes mass spectrometry data verifying the molecular weight of Melanotan II (CAS 121062-08-6). This dual-method approach — HPLC for purity and MS for identity — addresses the two most common disputes in peptide procurement: whether the material is pure enough and whether it is the material that was ordered. Raw data files are available upon request for laboratories that need to incorporate them into their own validation records. [NEED_CITE: mass spectrometry confirmation standards for synthetic peptide identity]
The stated impurity content of <0.1% reflects the integrated area of non-main peaks on the HPLC chromatogram. For formulators and researchers building assay systems, even minor related substances can interfere with receptor binding readings or alter solubility behavior during preparation. The endotoxin specification of ≤0.5 EU/μg is documented per batch using a validated assay, providing a baseline for laboratories that need to account for endotoxin load in cell-based experiments. Storage at -20 °C in sealed, light-protected containers preserves the lyophilized state; once reconstituted, stability shifts to approximately one month at 4 °C or six months at -20 °C, meaning aliquoting upon first reconstitution reduces degradation from repeated freeze-thaw cycles. The availability of 5 mg, 10 mg, and 15 mg vial sizes lets researchers order only what a trial requires, while bulk procurement from the same production line ensures specification continuity when scaling.
When a certificate of analysis does not name the analytical method, the buyer’s QC team must develop their own approach from scratch — and the resulting chromatogram may not match the supplier’s. This mismatch triggers a dispute cycle: re-test requests, sample exchanges, and retained-sample comparisons that delay research timelines by weeks. For importers, incomplete documentation packages — missing certificates of origin, absent safety data sheets, or inconsistent batch numbers across paperwork — hold shipments at customs with no resolution timeline. [NEED_CITE: common customs documentation requirements for peptide raw material import] Cold chain breaks during transit compound the problem: without a temperature log, there is no evidence to determine whether the lyophilized powder was exposed to conditions outside the validated storage range, leaving the receiving laboratory to decide whether to quarantine or discard an entire shipment.
Every batch of Melanotan II is produced with a retained sample held at the manufacturing site, enabling side-by-side re-testing if the buyer’s in-house analysis yields a different result. The certificate of analysis is not a generic template — it is generated per lot and states the HPLC method, column specification, and detection parameters used for that specific production run. Raw chromatogram files and mass spectrometry data are supplied alongside the certificate or provided on request, supporting method transfer and validation workflows. Cold chain packing includes temperature recording devices, so the transit history is documented from dispatch to delivery. Import documentation is prepared according to the destination country’s requirements before the shipment leaves, reducing the risk of customs delays. [NEED_CITE: retained sample protocols for peptide raw material suppliers] Free 1 mg samples with full testing documentation are available for laboratories that need to validate their analytical method before committing to a bulk order.
When placing an inquiry for Melanotan II (CAS 121062-08-6), specify the analytical method your laboratory uses for purity verification so we can confirm method alignment before dispatch. Indicate your required vial size, quantity, and whether you need raw HPLC and MS data files included in the documentation package. For international shipments, share your destination country’s import documentation requirements so the paperwork can be prepared in advance. If you are developing a new assay and need a sample for method validation before bulk purchase, request the 1 mg sample with full testing documentation.
Q: How is the certificate of analysis linked to the specific Melanotan II batch received?
A: Each certificate is generated per production lot and carries the exact batch number printed on the vial. The HPLC method conditions, column specification, UV detection wavelength, and MS parameters recorded on the certificate correspond to the testing performed on that specific batch. Retained samples from the same lot are held for post-delivery comparison if discrepancies arise during the buyer’s in-house verification.
Q: What analytical method is used to determine purity, and is the UV wavelength specified?
A: Purity is determined by reverse-phase HPLC with UV detection at 220 nm. The certificate states the column type, mobile phase composition, gradient profile, and flow rate used for the analysis. This level of detail allows the receiving QC laboratory to reproduce the chromatographic conditions and verify the reported purity value independently against their own instrumentation.
Q: What is the procedure if the buyer’s in-house HPLC result differs from the supplied COA?
A: We first compare the buyer’s method parameters with those stated on the batch certificate. If the methods differ, we provide raw chromatogram files and, if needed, re-test the retained sample using the buyer’s specified conditions. Most discrepancies trace to differences in column chemistry or gradient settings rather than actual batch variation, and method alignment typically resolves the issue.
Q: Are retained samples available for re-testing, and for how long?
A: Retained samples from every Melanotan II production batch are stored under validated conditions at -20 °C. These are available for re-testing or side-by-side comparison with the buyer’s received material. The retention period covers the full labeled shelf life of the product, supporting any verification needs that arise after delivery.
Q: What are the validated storage conditions and shelf life for lyophilized and reconstituted material?
A: Unopened lyophilized powder is stored at -20 °C, sealed and light-protected, with a shelf life of 24 months. After reconstitution, stability is approximately one month at 4 °C or six months at -20 °C. Aliquoting upon first reconstitution is recommended to minimize degradation from repeated temperature cycling.
All documents provided upon confirmed order. Contact us to request sample reports.
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